The Center for Disease Control breaks down MRSA infections as occurring in the community, and in healthcare settings.
When MRSA occurs in the community, it is usually a skin infection. While 1 in every 3 people carry staph in their nose (especially healthcare workers), about two in every 100 person carries MRSA.
Skin infections in the community are most likely to happen to athletes, in daycare/school settings, lockers rooms, etc. According to the CDC, "MRSA infection risk can be increased when a person is in certain actuates or places that involve crowding, skin-to-skin contact, and shared equipment or supplies. This might include athletes, daycare and school students, military personnel in barracks, and people who recently received inpatient medical care."
MRSA can also be acquired in healthcare settings. In the hospital, it can be spread from an infected wound or on the hands of a healthcare provider. It can become a very serious infection, especially if it spreads to the bloodstream.
There is good news though - the CDC has studied MRSA in the healthcare setting closely, and are finding from a variety of sources that the number of MRSA infections are declining. According to the CDC, "Invasive MRSA infections that began in hospitals declined 54% between 2005 and 2011, with 30,800 fewer severe MRSA infections. In addition, the study showed 9,000 fewer deaths in hospital patient in 2011 versus 2005." If you're interested in learning more about this data, you can find links to several studies at this webpage: http://www.cdc.gov/mrsa/healthcare/index.html#q1.
References:
http://www.cdc.gov/mrsa/community/index.html#q1
http://www.cdc.gov/mrsa/healthcare/index.html
http://www.naccho.org/topics/WBS/hai.cfm
http://en.wikipedia.org/wiki/Staphylococcus_aureus#/media/File:Staphylococcus_aureus_VISA_2.jpg
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